Is Progesterone really crucial to men’s health?
Dr. Lee reports in his book that, just as in women, men can suffer from the effects of “Estrogen Dominance” (an unnatural excess of it within one’s body). Estrogen excess results from an over- abundance of estrogen, estrogenic substances and steroidal growth hormones in the food we eat compounded by our exposure to petro-chemicals, solvents, pesticides and toxins in our modern environment.
Use Coupon Code “FIVEOFF” when ordering and get $5.00 off your order! Dr. John Lee, MD says up to this point the discussion has concerned the treatment of prostate cancer, but prevention is your best bet. The primary hormones that are prescribed for hormone replacement therapy (HRT) are derived from synthetic sources and do not have the same function in the body that our own biological hormones do. Per Dr. Lee, presently, natural progesterone (bio-identical hormone therapy) is beginning to get recognition for its beneficial effects for both Men and Women. Natural progesterone helps to counter balance the negative effects of estrogen. What are the Symptoms of Progesterone Deficiency in Women and Men as listed in Dr. Lee’s books? Symptoms in Women: Symptoms in Men: Furthermore, progesterone is a building block for many other hormones, including the corticosteroids, which are produced by the adrenal glands and are essential for stress response, electrolyte balance, blood pressure,
Dr. John Lee, MD says, just as with women, men can suffer from the effects of “Estrogen dominance” and reduced levels of progesterone caused by an over abundance of estrogen in the foods we eat and Xeno-estrogenic chemicals in our modern environment.
It is a significant factor in both prostate cancer and uterine cancer (nearly identical receptor cells). Research also shows that natural progesterone can counteract the toxic effects of estrogen dominance.
Dr. John Lee, MD says it can improve a man’s overall sense of well being and performance.
The adrenal and testes glands manufacture progesterone.
Adequate levels of progesterone are an integral part in maintaining a healthy prostate.
Yes, Dr. B. Formby, T.S.Wiley and Dr. John R. Lee have published their medical research on the importance of natural progesterone’s role in promoting Men’s good health & well being. Research also shows natural progesterone increases apoptosis – referred to as “the key to staying young.”
Dr. Lee’s book states that Prostate problems are the fastest-growing health concern among men in Westernized countries, and the rate of prostate cancer is increasing steadily.
Dr. John R. Lee, MD has received mail on the subject, and his responses aren’t always welcome news.
He explains that that prostate cancer becomes progressively more common with age, and that conventional treatments (surgical or chemical castration, radiation,
or surgical removal of the prostate) don’t do much good and in fact are likely to cause rather undesirable side effects.
The Journal of the American Medical Association (JAMA) of carried an article comparing treatment recommendations by radiation oncologists and urologists for men with moderately well differentiated, localized prostate cancer and greater than a 10-year life expectancy based on age.
In such cases, 92 percent of urologists recommend radical prostatectomy (removal of the prostate gland), whereas 72 percent of radiation oncologists recommend radiation treatments. An accompanying editorial points out that the treatment advice is determined by the services the doctor provides rather than by any clear-cut evidence of the superiority of either treatment, or even whether or not either treatment is any better than watchful waiting. And I (Dr. Lee MD) find it interesting that none of them recommended any nutritional or hormonal alternative management.
Dr. John Lee, MD says the value of PSA (prostate specific antigen) testing to detect prostate cancer, though touted as a proven strategy for early detection, is also questionable.
In Sweden, for example, physicians rarely screen for prostate cancer or use radical therapies, choosing watchful waiting instead.
Despite this, mortality rates for prostate cancer have declined in Sweden.
In the U.K., prostate cancer mortality rates are similar to the U.S. even though PSA screening is not routinely performed.
In older men, when prostate cancer occurs, the cancer is slow-growing and early intervention may be of little consequence.
In Dr Lee’s research, if radical treatments such as castration, radiation or prostatectomy are no better than watchful waiting, Dr. Lee, MD, believes it is time to reanalyze our underlying hypotheses concerning prostate cancer.
The present treatments are based on a “war” metaphor – find the abnormal cells and obliterate them by radiation or surgical removal.
Little thought is given to the underlying metabolic causes that change normal cells into cancer cells.
As with any disease, once the cause is identified, successful prevention and treatment strategies emerge.
Dr. John Lee, MD states that conventional medicine has fixated, despite lack of credible evidence, on testosterone as a presumed cause of prostate cancer.
When looking at the many studies that compared hormone levels with the occurrence of prostate cancer, there is no correlation with elevated testosterone levels.
If high testosterone levels caused prostate cancer, why don’t 18 year-old men get it?
The fact that some evidence shows a modest survival benefit from orchiectomy (castration) does not mean that testosterone reduction was the operative factor.
The testes make other hormones as well, and the observed prostate benefit of castration may stem from reducing one or another of them.
The role of estrogen dominance provides a more probable hypothesis. Estrogen dominance is the only known cause of endometrial (uterine) cancer.
The prostate is the male equivalent of the uterus; they both developed from the same embryonic cells.
They both contain the oncogene, Bcl-2, and the cancer-protective gene, p53.
And it has been shown that estradiol “turns on” p53 which blocks Bcl-2 in both breast cells and prostate cells.
This suggests that if the ration of testosterone to estradiol in men changes so that the estradiol effect becomes dominant, prostate cancer cells develop. Recent studies no find that this correlation is fact.
Dr. John Lee, MD points out that, Estrogen levels are rising in the general population in Westernized countries due to pervasive pollution of the environment by chemicals
that are estrogen mimics (aka xenoestrogens), such as pesticides, plastic residues and dozens of industrial chemicals such as dioxins and PCBs.
This is partially why most postmenopausal women need progesterone (to oppose or balance the estrogen), and it’s no doubt one reason that the incidence of prostate problems is increasing so rapidly in men.
Estrogen levels increase in aging men who are overweight because fat cells convert the male hormone androstenedione into estrogens, which then stimulates prostate growth.
Thus, the more fat a man carries on his body, the higher his estradiol levels are likely to be. Regular exposure to pesticides through spraying in the home or garden only adds to the problem.
Even if a middle-aged man’s testosterone levels are normal, if his estradiol levels are high he can have estrogen dominance symptoms
such as weight gain, larger-than-normal breasts, gall Bladder problems, anxiety and insomnia, and prostate enlargement that leads to urinary problems.
The crux of the present confusion about men’s hormones is the matter of achieving hormone balance.
Hormone balance refers not to absolute concentrations of any given hormone, but to the ration of one hormone with another.
It is the ratio of salivary concentrations of testosterone to estradiol that best reflects the hormone-related risk of prostate cancer.
those commonly rise a bit, and the ration of testosterone to estradiol falls.
Testosterone is a potent antagonist of estradiol and its effects on the body.
When testosterone levels decrease, estradiol becomes dominant.
Estradiol not only stimulates prostate cell proliferation but also activates the oncogene Bcl-2.
One by one, normal prostate cells become cancerous prostate cells.
This fits with findings of ultra-scans and prostate biopsies – the cancer cells are found in various small clusters here and there throughout the prostate, and not as a single prostate cancer mass.
If saliva tests find progesterone deficiency, progesterone supplementation is also indicated since it inhibits 5 alpha-reductase, the enzyme that converts testosterone to dihydrotestosterone (DHT).
High levels of DHT are correlated with prostate cancer.
Conventional treatments such as surgical or chemical (e.g., Lupron) castration stop the testes from making all sex hormones.
The observed cancer benefit is not due to testosterone reduction, but is more likely due to the decrease in estradiol production.
However, this approach sacrifices the potential benefits of testosterone and progesterone (men make small amounts of progesterone in their testes and adrenal glands).
Restoring physiologic levels of testosterone and progesterone to prevent estrogen dominance is a happier solution to the problem.
In addition to maintaining a healthy hormone balance with progesterone as mentioned above, prevention of prostate cancer undoubtedly involves other factors such as diet, specific nutrients, essential fatty acids, stress managements, and antioxidants. Whole foods such as broccoli and cabbage are attracting great interest as cancer fighters.
The nutritional advice on cancer that I give to women in the chapter in my “Premenopause” book also applies to men.
In conclusion, the conventional testosterone hypothesis is a 60 year-old mistake.
Present treatments are fraught with undesirable side effects and their purported benefits are little different than that of watchful waiting.
Extensive usage of PSA tests has done little to change prostate cancer mortality rates.
Fortunately, new studies teach us that estrogen dominance (a falling testosterone to estradiol ratio) may have a great deal to do with getting prostate cancer.
This is where we need to start.
Per Dr. Lee, historically, estrogen and how it affects us has been the most commonly talked about sex hormone.
However, the importance of progesterone, which is another type of sex hormone, has rarely been mentioned in the past.
Progesterone imbalance affects both women and men.
Scientific research is beginning to shed light on the importance of maintaining a balance between progesterone and estrogen for overall health and well being.
It is also beginning to show the significant differences between natural and synthetic progesterone.
Studies have shown that synthetic hormones are linked to an increase in certain types of cancer, strokes, and heart disease.
Reports of this study were released in The Jama report and BMJ Community Health Study .
According to Dr. John R. Lee, an authority on hormone balancing, “natural progesterone has a molecular structure identical to the progesterone produced by the human body
and is created through the fermentation process of the Mexican wild yam.” as used in Prosta-Health and ProgestaPlus crèmes.
Supplementing with a natural progesterone cream, such as ProgestaPlus or Prosta-Health for Men, can help correct hormonal imbalances that cause symptoms associated with
When there is not enough progesterone to counterbalance estrogen, one may begin to have symptoms of estrogen dominance.
For example, PMS, heavy or irregular periods, irritability, weight gain, anxiety, hair loss, low libido, fibrocystic breasts, endometriosis, and uterine fibroids, to name a few.
Men can experience many of these and other issues due to estrogen dominance.
• Hot Flashes
• Breast Tenderness
• Fibrocystic Breasts
• Hair Loss
• Bone Loss
• Low Libido
• Night Sweats
• Irregular Periods
• Vaginal Dryness
• Weight Gain
• Mood Swings
• Memory Lapses
• Loss of Muscle
• Excess Facial/Body Hair
• Heavy or Painful Periods
• Urinary Incontinence
• Poor Concentration
• Prostate problems
• Breast enlargement
• Bone/Muscle Loss
• Male patterned baldness
• Weight gain
• Low libido
and lastly, survival. Without adequate progesterone, synthesis of the cortisones is impaired and the body turns to alternate pathways.
These alternate pathways have masculine-producing side effects, such as long facial hairs and thinning of scalp hair. Cortisol, DHEA, testosterone,
and estrogen are all made from progesterone in a process that begins with cholesterol.
• Poor Liver Function
• Peri-menopause side effects
• Glandular Dysfunctions
• Environmental estrogens dominances.
As always, check with your doctor before you begin any hormone supplementation program.
Estrogens from environmental and food sources (xenoestrogens) can produce hormonal stimuli that can contribute to inappropriate growth of mammary tissue cells, resulting in a problem society is now calling “man boobs.”
• Promote healthy sex hormone balance
• Have a calming effect
• Help enhance mood
• Helps normalize menstrual cycles
• Increase sex drive
• Help use fat for energy
YDr. John Lee, MD points out the importance of explaining the difference between natural bio-identical progesterone and synthetic progesterone commonly known as Progestin, Provera, Primulut, and Duphaston.
The popular Premarin is a synthetic estrogen that is commonly used as another form of hormone replacement therapy for Men’s prostate treatments.
This pharmaceutical is made of synthetic estrogen without any synthetic progesterone added.
Even though there is a big difference between the effects of natural and synthetic progesterone, doctors often interchange their names.
Natural progesterone is not a patentable product; therefore, the pharmaceutical companies have altered this hormone to produce synthetic progestins,
which are patentable and are generally used in contraceptives and hormone replacement therapy (HRT).
For your overall health, we recommend you continue to learn about the benefits of natural bio-identical progesterone
and how it can help with hormonal imbalance without harmful side effects associated with synthetic progesterone.
Use Coupon Code “FIVEOFF” when ordering and get $5.00 off your order!
Dr. John Lee, MD says up to this point the discussion has concerned the treatment of prostate cancer, but prevention is your best bet.
The primary hormones that are prescribed for hormone replacement therapy (HRT) are derived from synthetic sources and do not have the same function in the body that our own biological hormones do.
Per Dr. Lee, presently, natural progesterone (bio-identical hormone therapy) is beginning to get recognition for its beneficial effects for both Men and Women.
Natural progesterone helps to counter balance the negative effects of estrogen.
What are the Symptoms of Progesterone Deficiency in Women and Men as listed in Dr. Lee’s books?
Symptoms in Women:
Symptoms in Men:
Furthermore, progesterone is a building block for many other hormones, including the corticosteroids, which are produced by the adrenal glands and are essential for stress response, electrolyte balance, blood pressure,
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